LIPOLOGICS Equivyn MetaNova Berberine LIPOSOMAL · HNOVA™ · 50–200 NM
Equivyn™ · MetaNova
Metabolic & Wellness

Liposomal Berberine

Plant alkaloid studied for metabolic and glucose-balance support. Supports metabolism, inflammation balance and overall wellness.

50–200 nm particle size Plant-based PC Nano liposomal encapsulation

Also searched as: berberine HCl, berberine liposomes

Specification, Certificate of Analysis and technical dossier available on request. Powered by the HNOVA™ platform.

Ingredient overview

What is Liposomal Berberine?

Liposomal Berberine is Berberine — an isoquinoline plant alkaloid, usually supplied as the hydrochloride salt — encapsulated in plant-based phosphatidylcholine (PC) liposomes on Hoynoza's HNOVA™ platform. The vesicles are nano-sized, 50 to under 200 nm, and are supplied as an ingredient for formulators and manufacturers.

Free Berberine presents a formulation challenge: it is only sparingly soluble in water and has limited membrane permeability. In a liposome, Berberine is carried in the core and bilayer, which is designed to protect the active and let it disperse evenly in the finished product.

Ingredient class: water- and fat-compatible · Brand: Equivyn™ (MetaNova) · Also searched as: berberine HCl, berberine liposomes

Core and bilayer
Water-soluble actives ride in the core while fat-soluble partners sit in the bilayer — one carrier for both.

Why liposomal berberine

From challenge to carrier

How the HNOVA™ liposome addresses the specific handling problem of Berberine.

The challenge

It is only sparingly soluble in water and has limited membrane permeability.

Free Berberine

The carrier

Berberine is entrapped in the core and bilayer of a 50 to under 200 nm plant-based phosphatidylcholine liposome.

HNOVA™ nano-liposome

The formulation benefit

Both partners travel together in one stable, dispersible carrier.

Designed outcome
Free Berberine versus Liposomal Berberine
Free active in waterCarried in liposomesclumps, settles, uneven doseuniform, dispersible vesicles
Illustrative schematic of dispersion behaviour, not measured data. Confirmed particle size and stability are reported per batch.
Why HNOVA™

Built on one platform, every time

Every Liposomal Berberine batch shares the same engineered advantages as the rest of the portfolio.

Enhanced Bioavailability

Improves absorption, increases cellular uptake and maximises systemic availability.

Superior Stability

Protects sensitive actives from oxidation, degradation, gastric enzymes and environmental stress.

Targeted Delivery

Nano-sized liposomes (50 to <200 nm) ensure precise delivery to target tissues and cells.

Improved Solubility

Enhances solubility of poorly water-soluble actives for better formulation flexibility.

Plant-Based & Clean Label

Developed using plant-based phosphatidylcholine (PC) for a premium, sustainable, clean-label delivery.

Comparison

Free Berberine versus Liposomal Berberine

What changes when the same active is carried in a liposome.

Free BerberineLiposomal Berberine (HNOVA™)
Dispersion in waterDepends on the raw-material form used.Carried as 50 to <200 nm vesicles that stay dispersed in water-based systems.
Protection of the activeExposed to oxygen, light and the surrounding medium.Held inside a lipid vesicle, away from the bulk medium.
Formulation challengeIt is only sparingly soluble in water and has limited membrane permeability.Addressed by encapsulation in the core and bilayer of the liposome.
CarrierNone — the raw material on its own.Plant-based phosphatidylcholine (PC).
LabelVaries by excipient system.Plant-based, clean-label lipid source.
Liposomal Berberine applications
Applications

Where Liposomal Berberine is used

Liposomal Berberine is supplied to formulators building products in the Equivyn™ family — metabolic & functional wellness. Typical formats and uses:

  • Liquid liposomal concentrates, shots and drops
  • Dried forms for capsules and sachets (confirmed per active)
  • Functional foods and beverages (formulation-dependent)
  • Metabolic and glucose-balance formulations
  • Inflammation-balance support
Specification

Liposomal Berberine — indicative parameters

ParameterDetail
IngredientLiposomal Berberine
Also known asberberine HCl, berberine liposomes
What it isAn isoquinoline plant alkaloid, usually supplied as the hydrochloride salt
Free-form characterWater- and fat-compatible
Carried inCore and bilayer
Particle size50 nm to <200 nm
Encapsulation typeNano liposomal encapsulation
Lipid sourcePlant-based phosphatidylcholine (PC)
BrandEquivyn™ · MetaNova
DocumentationSpecification sheet, CoA and technical dossier on request
Documentation

Available for this ingredient

Provided on request via the Contact page.

Certificate of Analysis

Per-batch particle size, encapsulation efficiency and purity results.

Specification sheet

Appearance, particle size, storage and format for this ingredient.

Technical dossier

Process, characterisation and stability notes.

Questions

Liposomal Berberine: common questions

What is Liposomal Berberine?

Liposomal Berberine is Berberine — an isoquinoline plant alkaloid, usually supplied as the hydrochloride salt — carried inside plant-based phosphatidylcholine liposomes. Lipologics supplies it as a nano-liposomal ingredient of 50 to under 200 nm, built on the HNOVA™ platform.

Why is Berberine encapsulated in liposomes?

Free Berberine presents a formulation challenge: it is only sparingly soluble in water and has limited membrane permeability. Carrying it in the core and bilayer of a nano-liposome is designed to protect the active and to disperse it evenly in the finished product.

Which formats can Liposomal Berberine be used in?

Typical routes are liquid liposomal concentrates, shots and drops, and dried forms for capsules and sachets. Format availability is confirmed per active — ask us for the format you need.

Is Liposomal Berberine a finished supplement?

No. Lipologics supplies Liposomal Berberine as an ingredient for formulators, manufacturers and product developers — not as a finished consumer product.

What documentation is available for Liposomal Berberine?

A specification sheet, Certificate of Analysis and technical dossier are available on request. Particle size and encapsulation efficiency are confirmed per batch.

Who supplies Liposomal Berberine in India?

Liposomal Berberine is supplied by Lipologics, the liposomal ingredient brand of Hoynoza Technologies Pvt Ltd, Bengaluru, India. Use the contact page to discuss specifications, samples and programme requirements.

Get in touch

Ask about liposomal berberine.