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HNOVA™ Platform

The science, made visible.

Every Lipologics ingredient is designed, developed and delivered exclusively using the proprietary HNOVA™ platform. Plant-Based. Nano-Smart. High Performance. Scroll to see how it works.

LIPOLOGICS
HNOVA™

All liposomal products, one platform

HNOVA™ integrates advanced nano-liposomal technology, deep scientific expertise and a commitment to quality to deliver high-performance liposomal solutions — engineered for absorption, designed for impact.

  • Plant-based phosphatidylcholine (PC) lipid source
  • Precision nano-encapsulation
  • Uniform 50–200 nm particle size
  • Scientifically developed & validated, every batch
Anatomy of a liposome

How a liposome carries an active

A liposome is a microscopic vesicle. Its structure lets one carrier hold both water-soluble and fat-soluble actives.

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  1. 1
    Phospholipid bilayer

    Two layers of plant-based phosphatidylcholine form the vesicle wall.

  2. 2
    Hydrophilic heads

    Water-loving heads face the outside and the inside of the vesicle.

  3. 3
    Lipophilic tails

    Fat-loving tails tuck together in the middle of the bilayer.

  4. 4
    Aqueous core

    Hydrophilic actives are carried in the water-filled centre.

  5. 5
    Embedded cargo

    Lipophilic actives sit within the bilayer itself.

Types of liposome

Unilamellar, large and multilamellar

Liposomes are classed by size and number of bilayers. HNOVA™ targets uniform nano-sized vesicles of 50 to under 200 nm.

Three liposome types
SUVSmall unilamellar vesicleOne bilayer · ≈20–100 nmLUVLarge unilamellar vesicleOne bilayer · ≈100–1,000 nmMLVMultilamellar vesicleOnion-like bilayers · ≈0.5 µm and up
Illustrative and not to scale. Size ranges are typical literature values.
How HNOVA™ Works

Five steps, start to finish

Step 01

Plant-Based PC Selection

High-quality plant-derived phosphatidylcholine (PC) is selected as the encapsulating lipid.

Step 02

Precision Encapsulation

Advanced nano-liposomal technology for optimal entrapment of the active ingredient.

Step 03

Nano-Sized Liposomes

Uniform liposomes formed in the 50 nm to <200 nm size range.

Step 04

Enhanced Delivery & Absorption

Liposomes enhance absorption, cellular uptake and targeted delivery to tissues.

Step 05

Maximum Results

Superior bioavailability leads to better efficacy and enhanced outcomes.

Platform Advantages

Why HNOVA™

Five advantages, engineered into every formulation on the platform.

Enhanced Bioavailability

Improves absorption, increases cellular uptake and maximises systemic availability.

Superior Stability

Protects sensitive actives from oxidation, degradation, gastric enzymes and environmental stress.

Targeted Delivery

Nano-sized liposomes (50 to <200 nm) ensure precise delivery to target tissues and cells.

Improved Solubility

Enhances solubility of poorly water-soluble actives for better formulation flexibility.

Plant-Based & Clean Label

Developed using plant-based phosphatidylcholine (PC) for a premium, sustainable, clean-label delivery.

Scale

How small is a nano-liposome?

HNOVA™ liposomes are 50 to under 200 nm — about the size of a virus and many times smaller than a bacterium, small enough to stay dispersed in liquids.

From a glucose molecule to a human hair
1 nm10 nm100 nm1 µm10 µm100 µmGlucose≈1 nmAlbumin protein≈7 nmInfluenza virus≈100 nmBacterium (E. coli)≈1–2 µmRed blood cell≈7 µmHuman hair≈70 µmHNOVA™ liposomes50 to <200 nmLogarithmic scale — each step is ten times larger. Sizes are approximate.
Reference sizes are approximate and shown for orientation only. Read more in our guide to liposome particle size.
Where the active sits

One carrier, two compartments

A liposome has a water-filled core and a fatty bilayer wall, so the same HNOVA™ platform can carry very different actives.

Water-soluble actives

Carried in the aqueous core, shielded from the surrounding environment.

Vitamin C · Glutathione · Minerals

Fat-soluble actives

Held within the phospholipid bilayer, so they disperse in water-based products.

CoQ10 · Carotenoids · Curcumin · Quercetin

Combination systems

Water- and fat-soluble partners in one carrier.

Vitamin C + K2 · Alpha-lipoic acid
Delivery pathway

Why the carrier changes the journey

A free active meets acid, enzymes and poor solubility on the way in. A liposomal active travels inside a lipid shell designed to keep more of the dose intact.

Conventional versus liposomal delivery
Conventional formatHNOVA™ liposomal format1Free activecapsule, powder or liquid2Digestive tractacid, enzymes, poor solubility3Gut walllimited uptake4Bloodstreamlower fraction arrives1Liposomal activevesicle-wrapped2Digestive tractlipid shell shields the cargo3Gut walldesigned for better uptake4Bloodstreamhigher fraction arrives
Illustrative schematic of design intent — line thickness is not measured data. Actual results depend on the active, formulation and dose. See liposomal vs non-liposomal.
Why liposomal

Conventional formats versus liposomal delivery

The differences a formulator notices first.

Conventional formatsHNOVA™ liposomal
AbsorptionOften limited by poor solubility and breakdown in the digestive tract.Improves absorption and increases cellular uptake.
StabilitySensitive actives can degrade with oxidation and environmental stress.Lipid vesicle protects actives from oxidation, degradation and gastric enzymes.
SolubilityPoorly water-soluble actives limit formulation options.Enhances solubility of poorly water-soluble actives; carries hydrophilic and lipophilic APIs.
DeliveryNon-specific release.Uniform 50 to <200 nm liposomes support precise delivery to target tissues and cells.
LabelVaries by excipient system.Plant-based phosphatidylcholine — clean-label lipid source.
Compatibility

Hydrophilic and lipophilic actives on one platform

The bilayer-and-core structure lets one carrier hold both.

Hydrophilic actives

Water-soluble actives — such as vitamin C, glutathione, minerals — are carried in the aqueous core, protected from the surrounding environment.

Lipophilic actives

Fat-soluble actives — such as CoQ10, carotenoids, curcumin — sit within the phospholipid bilayer, improving their dispersion in water-based systems.

Combination systems

Hydrophilic and lipophilic actives can be combined in a single liposomal system, for example paired vitamin and flavonoid formulations.

Formats

Delivered in the format your product needs

Format availability is confirmed per active.

Liquid

Water-dispersible liposomal liquids for shots, drops and beverages.

Powder

Dried liposomal forms for capsules, sachets and dry blends — formats confirmed per active.

Topical

Liposomal actives for serums, creams and other skincare bases.

By the numbers

One platform, measured consistently.

Every HNOVA™ batch is characterised against the same parameters, regardless of which of the 39+ actives it carries.

39+Actives on one platform
50–200nm particle size range
6Formulation categories
100% plant-based lipid source
Specifications

HNOVA™ platform specifications

ParameterDetail
Particle size50 nm to <200 nm
Encapsulation typeNano liposomal encapsulation
Lipid sourcePlant-based phosphatidylcholine (PC)
Delivery systemAdvanced nano-liposomes
CompatibilityHydrophilic & lipophilic APIs
Portfolio39+ actives across 6 formulation categories

Specifications above describe the HNOVA™ platform generally. Encapsulation efficiency, exact particle size and stability data are confirmed per active and per batch — request a specification sheet or Certificate of Analysis for the ingredient you are evaluating.

Science FAQ

Questions about the technology

What is a liposome?

A liposome is a microscopic vesicle formed from a phospholipid bilayer around a water-filled core. It can carry water-soluble actives in the core and fat-soluble actives within the bilayer.

Why plant-based phosphatidylcholine?

Phosphatidylcholine (PC) is the phospholipid that forms the vesicle wall. Plant-derived PC supports a clean-label, sustainable delivery system.

What particle size does HNOVA™ produce?

Uniform liposomes in the 50 nm to under 200 nm range. Exact size and distribution are confirmed per active and per batch.

How is encapsulation efficiency confirmed?

Encapsulation efficiency is characterised for every batch and reported in the Certificate of Analysis, alongside particle size and related parameters.

Can the same platform carry very different actives?

Yes — the same process applies across vitamins, antioxidants, carotenoids, peptides, minerals and more, with formulation details tuned per active.

Get in touch

Discuss a formulation programme.